The upcoming film Obvious Child embraces the romantic comedy genre, but takes on another identity as well: “abortion comedy.”
Romantic comedies surrounding an unplanned pregnancy are not new to film. Juno and Knocked Up are just a few films that create stories around this topic. However, Obvious Child tackles the same storyline but dares to take it in a new direction.
Director and writer Gillian Robespierre said she was, “rubbed the wrong way by the misrepresentation of women on screen when it came to unplanned pregnancy.”
Robespierre wanted to stray away from a movie in which the woman wavers between options, unable to make a decision. Instead, Donna Stern (Jenny Slate) immediately knows her own mind and chooses not consult the father (Jake Lacy). Donna rarely exhibits shame for her decision and she even pokes fun at it throughout the film.
Although Donna never questions her decision to have an abortion, her experience should not be taken lightly. “I think a lot of women feel like they have to be militant when it comes to abortion. We’re not just fighting for the right to have one, we’re fighting for the right to have a complex experience,” said Slate.
Robespierre does a phenomenal job at de-stigmatizing abortion by featuring various aspects of the experience, even the procedure itself, exclusively through Donna’s eyes.
[SPOILERS BELOW]
Following the procedure, the film concludes with Donna and Jake curling up for a movie, hand-in-hand. With smirks across both of their faces, Obvious Child creates a new image of “happily ever after.”
The National Action Center of the National Organization for Women (NOW) was given the opportunity to see an early screening of Obvious Child late last week. The film opens with a stand-up performance by Donna, including provocative jokes about her underwear that is so dirty at the end of the day it looks like “it climbed out of a tub of cream cheese.” The audience immediately keeled over in their seats, laughing hysterically, at the courageous honesty displayed throughout the film.
[Check here to see if there is a free showing in your area.]
“I just wanted to make sure Donna was lovable,” said Slate . “I’ve played a lot of characters people have to laugh at, but not necessarily love.”
I think that’s what makes Obvious Child such a successful, challenging film for a variety of audiences. Slate creates a relatable and lovable character through her honest comedy. The film could really appeal to all audiences, even if her portrayal of abortion does not. Robespierre builds up the character of Donna Stern in an endearing light, capturing the audience’s heart and challenging them to look at abortion in an extremely unique way.
The character execution of Jenny Slate combined with the storytelling of Gillian Robespierre make Obvious Child a potential game-changer in how abortion is represented in the media.
Obvious Child hits theaters Friday, June 6.
Yes to the strength of a woman.
I was told there would be a pass for a screening in Memphis at this page.
Closer to home and would like to see it
Yes i would like passes for this
Let’s see how this goes!
this look like a really good movie that i would love to go see.
2 Screening Tickets, please.
Look forward to seeing this.
We all need more laughs!
grabbing passes… codes? thanks!
Need to see this one
How d o I get a code for passes?
LOOKING FORWARD TO SEEING THIS FILM. CURIOUS HOW THEY DEAL WITH SUCH A DIFFICULT SUBJECT.
Looks great
Need passes for obvious child
I would love tickets
Looking for a ticket to Obvious Child
The movie’s premise intrigued me and I’d love to support films that deserved to be seen
How can I get a pass to this preview for Monday June 23 in Santa Clara?
Thanks so much.
I would love to see Obvious Child at the Indianapolis screening June24th. Thank you
This type of story could be every woman’s story.
This is a great story line and can’t wait to see it!
This looks like an awesome movie…can’t wait to see…
Maryland NOW is co-hosting a screening of this film in Baltimore. Come one, come all. https://www.facebook.com/events/578891788898786/
Glad to see MD NOW getting in on the Obvious Child action. Enjoy — it’s a great movie!
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Ipamorelin and sermorelin are both peptide compounds that stimulate the release of growth hormone from the pituitary gland, but
they differ in their chemical structure, potency, duration of action, side-effect profile,
and clinical applications. Understanding these distinctions is essential for healthcare providers who prescribe
peptide therapy as well as for patients considering or
already using these agents to improve body composition, recovery, or overall health.
What Is the Difference Between Ipamorelin and Sermorelin?
Chemical Structure and Mechanism of Action
Sermorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH).
It mimics the natural ligand for the GHRH receptor on pituitary somatotrophs, thereby triggering
endogenous growth hormone secretion. Ipamorelin, in contrast, belongs to the class of growth
hormone secretagogues that act as ghrelin receptor agonists, specifically targeting the growth hormone secretagogue
receptor (GHSR). While both peptides ultimately increase circulating growth hormone
levels, they do so through distinct receptors and signaling pathways.
Potency and Duration
Sermorelin has a relatively short half-life of about 15–20 minutes.
To maintain adequate stimulation, it is typically administered in multiple
daily injections or as a continuous infusion over several hours.
Ipamorelin’s action lasts longer—approximately one to two hours per dose—allowing for fewer administrations
while still producing a robust growth hormone surge.
This difference translates into practical advantages: patients who prefer once-daily dosing may
find ipamorelin more convenient, whereas sermorelin can be tailored with frequent injections or infusion pumps to
fine-tune hormone release.
Side-Effect Profile
Because sermorelin is structurally similar to
the natural GHRH peptide, it usually has a low incidence of side
effects. Commonly reported issues include mild injection site discomfort and transient
headaches. Ipamorelin’s activation of ghrelin receptors can cause appetite
stimulation in some users; however, ipamorelin is often praised for having minimal adverse reactions compared
with other secretagogues such as growth hormone-releasing peptide-2 (GHRP-2)
or growth hormone-releasing peptide-6 (GHRP-6). Nonetheless, both peptides may occasionally lead to mild
swelling at the injection site and, rarely, increased thirst.
Clinical Uses
Sermorelin is frequently prescribed for diagnosing
growth hormone deficiency in children and adults. It can also be employed
therapeutically to enhance growth hormone production in patients with proven deficiencies or as part of
anti-aging protocols. Ipamorelin is more commonly used within body-building
circles and among individuals seeking improved
recovery, increased lean muscle mass, and fat loss without the appetite increase associated with other ghrelin agonists.
In clinical research, ipamorelin has been studied for its potential benefits in wound healing, muscle wasting disorders, and sleep quality.
Understanding Peptide Therapy and Growth Hormone Stimulation
Peptides are short chains of amino acids that can modulate biological processes by binding to specific receptors.
In the context of growth hormone therapy, peptide agents either directly stimulate the pituitary gland (as with sermorelin) or mimic signals from other tissues such as the stomach (as with
ipamorelin). The central idea is to create
a physiological surge in growth hormone that mimics the natural circadian rhythm—high during sleep and lower during wakefulness.
Administration Routes
Both peptides are typically delivered via subcutaneous injection. The dosage for sermorelin often ranges from 0.2
to 1 mg per day, split into multiple injections or an infusion pump set at a constant rate of 10–15 micrograms per hour.
Ipamorelin is usually prescribed in doses between 200 and 500 micrograms,
administered once or twice daily depending on the desired effect.
Some patients use ipamorelin before sleep to maximize nighttime growth hormone release.
Monitoring Efficacy
To gauge peptide therapy effectiveness, clinicians monitor serum levels of growth hormone and insulin-like growth factor-1
(IGF-1), a downstream marker that reflects sustained GH activity.
In addition, body composition scans, bone density measurements, and metabolic panels can help
assess the therapeutic impact over time. Adjustments in dosage or
frequency are guided by these objective data points.
Safety Considerations
Long-term safety data for both peptides are limited compared with recombinant
human growth hormone. However, because they stimulate endogenous production rather
than delivering exogenous hormone directly, the risk of receptor down-regulation and resistance may be lower.
Patients should still undergo regular endocrine evaluations to detect any abnormalities such as
hypoglycemia, joint pain, or edema.
Can Ipamorelin and Sermorelin Be Used Together?
Theoretically, combining a GHRH analogue with a ghrelin receptor agonist
could produce additive effects on growth hormone secretion because they activate different pathways.
In practice, however, the evidence supporting simultaneous use is sparse.
Some anecdotal reports from body-building communities suggest that pairing ipamorelin with sermorelin may
enhance peak GH levels and prolong the hormone surge.
Nonetheless, clinicians typically advise against concurrent
administration unless a clear therapeutic rationale exists, primarily due to
concerns about overstimulation, unpredictable side effects, or unnecessary cost.
Clinical Trials and Case Reports
A few small studies have examined co-administration in animal models, showing increased growth
hormone output compared with either agent alone. Human data remain limited;
most research focuses on single-agent protocols.
Therefore, any decision to combine ipamorelin and sermorelin should be
made cautiously, under close medical supervision, and
with thorough documentation of dose, timing,
and patient response.
Practical Considerations
If a practitioner chooses to use both peptides together, careful scheduling is required
to avoid overlapping peaks that might lead to excessive hormone levels.
For example, a typical protocol might involve administering sermorelin in the early evening as part of an infusion, followed
by a single ipamorelin injection at bedtime. This approach aims to
mimic natural circadian patterns while maximizing therapeutic benefit.
In summary, ipamorelin and sermorelin share the common goal of elevating growth hormone levels but differ
markedly in their molecular targets, pharmacokinetics,
dosing convenience, side-effect profiles, and clinical indications.
Peptide therapy offers a nuanced method for modulating endocrine function, yet it demands meticulous monitoring and individualized planning.
While combining ipamorelin and sermorelin is theoretically
possible, evidence for its efficacy and safety remains limited; therefore, such an approach should dianabol only cycle before and after be pursued when justified by clear medical objectives and performed under professional guidance.
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Plus, they’ve a team of experts on hand to answer any questions you may
have. They also supply free worldwide delivery (including the United States, UK, France, India, Germany,
Europe & Australia), and each third item is free. It also
helps to preserve muscle mass when you’re chopping calories, so you don’t have to fret about dropping the progress you’ve made.
Anavar additionally boosts purple blood cell production, resulting in improved
endurance and vascularity. There have been no research
conducted on mixing grapefruit juice with oral anabolic steroids; nevertheless, anecdotally, we have seen this work.
However, if users are going to drink grapefruit juice orally,
they have to be cautious of overdosing, as 50 mg of Anadrol might effectively double with the inhibition of CYP3A4.
In order to get well endogenous testosterone manufacturing, an aggressive
PCT protocol ought to be administered. This is especially true if a consumer is stacking Anadrol with different anabolic
steroids. Anadrol has legendary standing within the bodybuilding and powerlifting
world for good causes.
As A End Result Of it may possibly harm the liver, it’s
important to be careful with how a lot and the way lengthy it is used.
Still, many select it Time Frame for Results with Extreme Stack the most important muscle gains they can get throughout a bulking cycle.
This, combined with a good diet and train program, can lead to increased muscle mass,
improved definition, decreased physique fat, and more testosterone.
SARMs (Selective Androgen Receptor Modulators) are
compounds with a similar construction and function to anabolic
steroids but with fewer and milder side effects.
Adults generally obtain 5 to 10 mg of oxandrolone every day in 2-4 divided doses for 2-4 weeks, with a maximum of 20
mg/day in select catabolic states.
This may help negate some of the adverse effects of Anadrol (including pressure
on the heart). Our patients have discovered that drinking lots
of water and sustaining a clear food regimen successfully prevents water
retention. When a person drinks more water, it causes the body
to flush out current water within the physique as a self-defense mechanism.
We have not come across a trio of steroids that produce the identical level of energy and mass as these.
As this is an oral steroid, some bodybuilders have been recognized to swallow Anabol
tablets on an empty abdomen. Anabol causes lots of bloating
so just bear that in mind as it may possibly
make you’re feeling uncomfortable, plus you will
look very swollen, which makes it one of the powerful weight achieve steroids.
One reason why Anabol is considered to be so well-liked on the planet of bodybuilding is that of the fact that it provides far fewer unwanted aspect effects to customers than other extra highly effective steroids.
Anabol is also referred to as methandrostenolone and it is considered one
of the most potent oral steroids presently in the marketplace.
Anabol is doubtless considered one of the best steroids for anybody seeking to make some
serious positive aspects and take their physique up a stage.
Different advantages of Anavar include enhancing stamina and energy as a outcome of it boosts pink blood cells.
The joint advantages of Anavar make it stand out above other cutting steroids and is considered one of my
favorite issues about Anavar. Despite its status as a highly effective steroid,
it’s still a comparatively gentle oral compared with other compounds.
Anavar is properly known as the only anabolic steroid
women can use with little to no danger of unwanted effects – as lengthy as doses
don’t exceed 20mg per day.
Concomitant administration with adrenal steroids or ACTH might add to the edema.
This is usually controllable with appropriate diuretic and/or digitalis remedy.
ANADROL Tablets is indicated in the remedy of anemias attributable to poor red cell manufacturing.
As A Result Of it’s a lengthy ester, it doesn’t have an immediate effect and takes a quantity of weeks to peak within the blood.
But with extended cycles and moderate doses,
Deca could be very effective at adding a average quantity
of muscle and is an underrated bulking steroid.
If a bodybuilder measures muscle mass achieve success purely by weight gain, Trenbolone just isn’t one of the best steroid to take.
Nevertheless, if a bodybuilder measures muscle mass
acquire success by what they see in the mirror, Trenbolone would be the
first anabolic compound. Inside drugs, Anavar has been utilized for instance in AIDS sufferers throughout the range
of 20 – 80mg per day in order to fight and/or reverse muscle wasting[6].
This is a stable indication of the final dosage range that might be effective for muscle growth and
athletics. As Anavar is a drug with plenty of expertise with different ages of sufferers,
the results of Anavar are also not depending on age[8].
Also people who find themselves worried
about steroid’s unwanted effects are more inclined to take anavar as the dangers are lower.
Outdoors of the united states, some international locations permit it to be prescribed for individuals with asthma or respiration problems.
Some athletes and bodybuilders misuse clenbuterol to lose fats and achieve muscle.
They could take two to 3 instances the quantity prescribed to these with
asthma. Critical unwanted effects might happen, sometimes
leading to hospitalization.
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You can easily turn into psychologically depending on anabolic steroid use (meaning
you develop an increased tendency to maintain taking the drug even despite possible harmful
effects). Stacking is a sample of use of taking two or extra oral or injectable forms of steroids in hopes of better outcomes.
Doses are variable and could also be many instances the dose given therapeutically for varied medical
situations. In sure cases of addiction, patients have taken medicines to help deal
with symptoms of withdrawal. For example, well being care suppliers have prescribed antidepressants to deal with depression and ache medicines for complications and muscle and joint ache.
Other medicines have been used to assist restore the patient’s hormonal
system.
Steroids are in style for their capability to significantly
improve muscle measurement and athletic talents.
Customers see features in strength and stamina, which lets them transcend
their limits. Such muscle development is not only for
looks; it really helps athletes perform higher. A one that is hooked on anabolic steroids will want to maintain utilizing them regardless of experiencing disagreeable bodily unwanted effects.
Many of the unwanted effects are the identical for women and men,
Smit says. Males on anabolic steroids may expertise baldness, breast development, and shrinking testicles, in accordance
with MedlinePlus. This is the persona change one could experience as a outcome of taking anabolic steroids.
Many individuals find themselves turning into hostile, experiencing main temper swings, and fascinating in aggressive conduct, per the DEA.
This can typically lead to melancholy and suicide as quickly as the
steroids have been stopped. Novice bodybuilders typically ponder whether or not to choose on oral or injectable anabolic
steroids. Zits is a standard side effect that roughly 50% of bodybuilders experience as a result of utilizing anabolic steroids (25).
Others, like the TikToker Caroline Mathias (34,000 followers)
are calling out steroid drug use by well-liked social media personal-trainer influencers.
When the oil hits a vessel, international metabolites enter the lungs; thus, the
physique coughs as a self-defense mechanism to expel such substances.
Due To This Fact, our patients could not make
the most of a liver support supplement (such as TUDCA or milk thistle) when biking injectables.
Injectable steroids are administered deep into the muscle,
generally identified as intramuscular injections. These are typically performed in the buttocks or the
outer thigh.
The solely other noteworthy competitor on social media was SDI Labs, with 2,994 Facebook fans,
and Flexx Labs, with 1,671 followers. Crazy Bulk is the main retailer
of legal steroids online, selling over 500,000 bottles.
Inform your well being care provider when you have any of the following.
While less frequent, the most critical unwanted side effects of oxandrolone are
described under, together with what to do in the event that they
happen.
LDL is the negative type of cholesterol that may clog arteries when high, leading to
a spike in blood strain. During the 60s/70s era, bodybuilders might simply go to their docs and ask for Dianabol (and other steroids) to
get greater and stronger, and their request would be granted.
Steroids’ adverse results weren’t well known, and they were 100% legal.
In some circumstances, corticosteroids may actually cause muscle loss when used long-term.
When taken as prescribed, steroids have a risk of gentle short-term unwanted effects.
Thus, as you have no idea the date of the test, it’s doubtless you’ll
fail. Anavar is predominantly used during cutting cycles as a
result of its fat-burning effects and being a dry steroid
with no water retention. Anadrol, however, is a moist steroid because of its
estrogenic nature. Both are efficient for including lean mass and growing power; nonetheless, Anadrol will produce more water retention.
An overdose can be reversed if opioid overdose reversal medications, together with naloxone (sometimes
bought as Narcan®), are given rapidly. The results of methylphenidate include increased wakefulness and vitality.
Loperamide may cause feelings of rest or happiness, just like other opioids.
Some folks use it to minimize opioid cravings and withdrawal signs.
Restricted analysis suggests that taking ibogaine does not typically lead to a substance use dysfunction. Heroin is
an opioid drug created from morphine, a pure substance taken from the seed
pod of the assorted opium poppy crops grown in Southeast and Southwest
Asia, Mexico, and Columbia.
References:
Methandrostenolone history